Short Answer: No
Long Answer: You must include audio — from 508 requirements — “ICT with a display screen shall be speech-output enabled for full and independent use by individuals with vision impairments.” https://www.access-board.gov/ict/#402.2
There are a number of methods for providing speech output. One method is by screenreader, but there are others.
Plain English example: If someone asks me if screen reading software is mandatory for a kiosk application to meet 404.2, I would say “no” and explain that the regs do not specify how the manufacturer meets the 404.2. They might use screen reading software, or they might use a different technical approach.